08. PTC: Cancer Risks for Kidney Recipients

08. PTC: Cancer Risks for Kidney Recipients

For kidney recipients, a recent study gives some statistics of risk post-transplant by way of introduction to the topic.  While this paper may be more detailed and and scientific for the average reader, one can certainly get the gist of conern level in its research summary that is quoted in "Independent Pre-Transplant Recipient Cancer Risk Factors after Kidney Transplantation and the Utility of G-Chart Analysis for Clinical Process Control" (<-- click on the title to link to the full reseach paper) shown here:

"Cancer incidence rates were almost three times higher as compared to the matched general population (SIR = 2.75; 95%-CI: 2.33–3.21). Significantly increased SIRs were observed for renal cell carcinoma (SIR = 22.46), post-transplant lymphoproliferative disorder (SIR = 8.36), prostate cancer (SIR = 2.22), bladder cancer (SIR = 3.24), thyroid cancer (SIR = 10.13) and melanoma (SIR = 3.08). Independent pre-transplant risk factors for cancer-free survival were age <52.3 years (p = 0.007, Hazard ratio (HR): 0.82), age >62.6 years (p = 0.001, HR: 1.29), polycystic kidney disease other than autosomal dominant polycystic kidney disease (ADPKD) (p = 0.001, HR: 0.68), high body mass index in kg/m2 (p<0.001, HR: 1.04), ADPKD (p = 0.008, HR: 1.26) and diabetic nephropathy (p = 0.004, HR = 1.51). G-chart analysis identified relevant changes in the detection rates of cancer during aftercare with no significant relation to identified risk factors for cancer-free survival (p<0.05)."



Stay tuned as we develop this kidney topic further...

Most Common Post-Transplant Cancer Types

Updated: 3/11/2020 JMG

Each type of organ transplant comes with cancer risks that may be different due to the unique biology of that organ, or more commonly, due to the different drug protocols - both drug type and dosage - used for each transplant.  

In this LOOK section,...

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    DISCLAIMER: The content of this TRIO post-transplant cancer Web site is not influenced by sponsors. The site is designed primarily for use by transplant recipients and their supporters. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with your transplant team or a physician skilled in cancer and your organ type if you suspect you are ill.